HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tetrahydrofuran → HCID 178499190, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tetrahydrofuran | HCID 8028 | — |
| Reactant | Thiourea | HCID 2723790 | — |
| Reactant | 1,2,4-Thiadiazole-3-carboxylic acid, 5-chloro-, methyl ester | HCID 23324199 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 178499190 | HCID 178499190 | 92.4% |
Reaction Steps
A mixture of methyl 5-chloro-1,2,4-thiadiazole-3-carboxylate (7.80 g), thiourea (3.32 g), tetrahydrofuran (24 ml) and water (8 ml) was gently boiled for 6.5 hours. The reaction mixture was post-treated according to conventional manner to give yellow powder of methyl 5-mercapto-1,2,4-thiadiazole-3-carboxylate (7.1 g), mp. 126° to 127° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04268509 |
| Source dataset | uspto-grants-1981_05 |
| ORD ID | ord-8ef32de6afba4bcfbacf035a7ffc4d05 |
| Source note | uspto-grants-1981_05 |