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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 228702Generated: October 30, 2026

Hydrochloride methanol → HCID 68828808, compound

https://huagongshe.com/reaction/228702

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloride methanolHCID 21893726—
ReactantHCID 24879270HCID 24879270—
ProductHCID 68828808HCID 6882880810%

Reaction Steps

1-[2-(6,7-Dimethoxy-quinolin-4-yloxy)-5-methoxy-phenyl]-ethanone (802 mg) was dissolved in a hydrochloric acid-methanol solution (20 ml) to prepare a solution which was then stirred at room temperature overnight. The solvent was removed by distillation under the reduced pressure, and the residue was washed with ethyl acetate and was dried in vacuo to give the title compound (885 mg, yield 10%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07560558B2
Source datasetuspto-grants-2009_07
ORD IDord-dd4b7784496c484597ddfe3f571fcfa8
Source noteuspto-grants-2009_07