Hydroxyamine hydrochloride → HCID 12876705, compound

Participants

Reaction Steps

4-[(2-Chloro-4-methoxyphenyl)methyl]-3,5-diethylisoxazole [I; Ar is 2-Cl-4-CH3OC6H3, Y is CH2, R is C2H5 ] was prepared from 30.9 g. of 4-[(2-chloro-4-methoxyphenyl)methyl]-3,5-heptanedione and 7.96 g. of hydroxylamine hydrochloride in 65 ml. of pyridine according to the procedure of Example 2, part (b), and was obtained in the form of a pale yellow oil, b.p. 144°-147° C. (0.08 mm.); yield 21.6 g.; MIC=12 μg/ml (herpes 2).

Provenance & Evidence