Hydroxyamine hydrochloride → HCID 5271170, compound

Participants

Reaction Steps

3,5-Diethyl-4-[6-(4-methoxy-2-nitrophenoxy)hexyl]isoxazole [I; Ar is 2-O2N-4-CH3OC6H3, Y is O(CH2)6, R is C2H5 ] was prepared from 10.0 g. of 4-[6-(4-methoxy-2-nitrophenoxy)hexyl]-3,5-heptanedione and 2.0 g. of hydroxylamine hydrochloride in 40 ml. of pyridine according to the procedure of Example 2, part (b), and was obtained in the form of a yellow oil, b.p. 200°-205° C. (0.02 mm.); yield 7.5 g.; MIC=3 μg/ml (herpes 2).

Provenance & Evidence