Hydroxyamine hydrochloride → HCID 13078362, compound

Participants

Reaction Steps

4-[4-(2-Chloro-4-methoxyphenoxy)butyl]-3,5-diethylisoxazole [I; Ar is 2-Cl-4-CH3OC6H3, Y is O(CH2)4, R is C2H5 ] was prepared from 16.2 g. of 4-[4-(2-chloro-4-methoxyphenoxy)butyl]-3,5-heptanedione and 3.3 g. of hydroxylamine hydrochloride in 65 ml. of pyridine according to the procedure of Example 2, part (b), and was obtained in the form of a yellow oil, b.p. 180°-190° C. (0.1 mm.); yield 9.3 g.; MIC=6 μg/ml (herpes 2).

Provenance & Evidence