HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(2-Chloroethyl)morpholine → 4-(3-piperazino)propyl-4H-pyrazolo[4',3':5,6]pyrido[3,4-e][1,2,4]triazolo[1,5-a]pyrimidin-5(8H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(2-Chloroethyl)morpholine | HCID 76727 | — |
| Reactant | 1-(3-Chloropropyl)piperazine | HCID 577606 | — |
| Reactant | 4H-pyrazolo[4',3':5,6]pyrido[3,4-e][1,2,4]triazolo[1,5-a]pyrimidin-5(8H)-one | HCID 135593853 | — |
| Product | 4-(3-piperazino)propyl-4H-pyrazolo[4',3':5,6]pyrido[3,4-e][1,2,4]triazolo[1,5-a]pyrimidin-5(8H)-one | HCID 23459584 | — |
Reaction Steps
By substituting 3-piperazinopropyl chloride for the 1-chloro-2-morpholinoethane in the procedure of Example 8 and utilizing the 4H-pyrazolo[4',3':5,6]pyrido[3,4-e][1,2,4]triazolo[1,5-a]pyrimidin-5(8H)-one product of Example 11, 4-(3-piperazino)propyl-4H-pyrazolo[4',3':5,6]pyrido[3,4-e][1,2,4]triazolo[1,5-a]pyrimidin-5(8H)-one is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04269836 |
| Source dataset | uspto-grants-1981_05 |
| ORD ID | ord-19214faf19be43a1b0f0fba8751de0e9 |
| Source note | uspto-grants-1981_05 |