Phthalimide potassium salt → HCID 86737751, compound

HRID 2287216Notes

Reaction equation

HRID 2287216 reaction equation
[Cl:1][C:2]1[CH:25]=[CH:24][CH:23]=[CH:22][C:3]=1[NH:4][C:5](=[O:21])[CH:6]([C:8](=[O:20])[C:9]1[CH:14]=[C:13]([N+:15]([O-:17])=[O:16])[C:12]([O:18][CH3:19])=[CH:11][CH:10]=1)Br.[K].[C:27]1(=[O:37])[NH:31][C:30](=[O:32])[C:29]2=[CH:33][CH:34]=[CH:35][CH:36]=[C:28]12>CN(C)C=O>[Cl:1][C:2]1[CH:25]=[CH:24][CH:23]=[CH:22][C:3]=1[NH:4][C:5](=[O:21])[CH:6]([C:8](=[O:20])[C:9]1[CH:14]=[C:13]([N+:15]([O-:17])=[O:16])[C:12]([O:18][CH3:19])=[CH:11][CH:10]=1)[N:31]1[C:30](=[O:32])[C:29]2=[CH:33][CH:34]=[CH:35][CH:36]=[C:28]2[C:27]1=[O:37]

Participants

4

Reactant 2

HCID 24194345Phthalimide potassium saltHCID 86737752HCID 86737752, compound

Product 1

HCID 86737751HCID 86737751, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

A mixture of 30 g of 2'-chloro-4-methoxy-5-nitro-α-bromo-benzoylacetanilide and 39 g of phthalimide potassium was stirred in 400 ml of dimethylformamide for 3 hours at room temperature. The reaction product was treated as in Synthesis example 1. Upon recrystallizing the product from methyl cellosolve, 14 g of the Coupler 33 having a melting point of 203°-205° C. was obtained.

Workup

  1. additionThe reaction product was treated as in Synthesis example 1
  2. customUpon recrystallizing the product from methyl cellosolve, 14 g of the Coupler 33 having a melting point of 203°-205° C.
  3. customwas obtained

Sources & evidence

ORD record
ord-5496273e153d418696b9665136d75b44
Source dataset
uspto-grants-1981_05
Patent number
US04269936

Reaction notes

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