Methanol, 1,1-diethoxy-, 1-acetate → HCID 13017518, compound

HRID 2287221Notes

Reaction equation

HRID 2287221 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[C:9]([NH:14][NH2:15])=[N:10][CH:11]=[N:12][CH:13]=2)=[CH:4][CH:3]=1.[C:16](OC(OCC)OCC)(=O)C>CCCCCC>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]2[C:9]3[N:10]([CH:16]=[N:15][N:14]=3)[CH:11]=[N:12][CH:13]=2)=[CH:6][CH:7]=1

Participants

4

Reactant 2

HCID 84166Methanol, 1,1-diethoxy-, 1-acetateHCID 13017517HCID 13017517, compound

Product 1

HCID 13017518HCID 13017518, compound

Reagents, catalysts & solvents 1

HCID 8058HexaneSolvent

Procedure

A mixture of 2.0 g. of 5-(4-chlorophenyl)-4-hydrazinopyrimidine is shaken with 10 ml. of diethoxymethyl acetate. The mixture is allowed to stand 15-30 minutes and then is diluted with hexane. The precipitated product (1.81 g: 83%) is collected and recrystallized from ethanol to give the title compound; m.p. 193°-195° C .

Workup

  1. additionA mixture of 2.0 g
  2. customThe precipitated product (1.81 g: 83%) is collected
  3. customrecrystallized from ethanol

Sources & evidence

ORD record
ord-93a9b87f16174698ac2065b3be6c13a3
Source dataset
uspto-grants-1981_05
Patent number
US04269980

Reaction notes

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