Benzyl Bromide → HCID 23459840, compound

HRID 2287275Notes

Reaction equation

HRID 2287275 reaction equation
[O:1]=[C:2]1[N:9]2[C:4]([CH3:12])([CH2:5][CH2:6][O:7][C:8]2([CH3:11])[CH3:10])[CH:3]1[CH:13]([CH3:15])C.C(Br)[C:17]1[CH:22]=[CH:21]C=[CH:19][CH:18]=1>>[O:1]=[C:2]1[N:9]2[C:4]([CH3:12])([CH2:5][CH2:6][O:7][C:8]2([CH3:10])[CH3:11])[CH:3]1[CH2:13][C:15]1[CH:21]=[CH:22][CH:17]=[CH:18][CH:19]=1

Participants

3

Reactant 2

HCID 7498Benzyl BromideHCID 23459827HCID 23459827, compound

Product 1

HCID 23459840HCID 23459840, compound

Procedure

Following the procedure described for the preparation of 8-oxo-3-oxa-2,2,6-trimethyl-7-isopropyl-1-azabicyclo[4.2.0]octane from 8-oxo-3-oxa-2,2,6-trimethyl-1-azabicyclo[4.2.0]-octane (Example 4a, above) and using benzyl bromide instead of isopropyl iodide there is obtained 8-oxo-2,2,6-trimethyl-7-benzyl-3-oxa-1-azabicyclo[4.2.0]octane.

Sources & evidence

ORD record
ord-79f2a63ad50c494d9e132f2aa65ce3f7
Source dataset
uspto-grants-1981_05
Patent number
US04269873

Reaction notes

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