Triethylamine → HCID 53915928, compound

HRID 2287658Notes

Reaction equation

HRID 2287658 reaction equation
[Br:1][C:2](Br)=[CH:3][C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[C:10]([F:13])([F:12])[F:11].CCN(CC)CC>CCCCCC>[Br:1][CH:2]=[CH:3][C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[C:10]([F:11])([F:12])[F:13]

Participants

4

Reactant 2

HCID 8471TriethylamineHCID 10782611HCID 10782611, compound

Product 1

HCID 53915928HCID 53915928, compoundYield 90%

Reagents, catalysts & solvents 1

HCID 8058HexaneSolvent

Procedure

A solution of 1-(2,2-dibromo-vinyl)-2-trifluoromethyl-benzene (989 mg, 3 mmol), and Et)2POH (0.75 ml, 6 mmol) in Et3N (0.83 ml, 6 mmol) was stirred at 5° for 4 h. Hexane was added, and stirred for further 10 min. The mixture was extracted with hexane, washed with brine and dried over Na2SO4. Evaporation of the solvent and chromatography (hexane) gave 1-(2-bromo-vinyl)-2-trifluoromethyl-benzene (674 mg, 90%) as a colorless liquid. IR (KBr): 1600, 940 cm-1. MS (EI): 251 (M).

Workup

  1. extractionThe mixture was extracted with hexane
  2. washwashed with brine
  3. dry with materialdried over Na2SO4
  4. customEvaporation of the solvent and chromatography (hexane)

Sources & evidence

ORD record
ord-acc77194f86544eaa82a111b5121f97e
Source dataset
uspto-grants-2000_07
Patent number
US06084120

Reaction notes

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