Hydrochloric Acid → HCID 18705822, compound

Participants

Reaction Steps

Using procedure 51, 2-(dipropylamino)-2,3-dihydro-1H-indene-5,6-dicarboxylate (92, 0.349 g, 1 mmol) was treated with benzylhydrazine dihydrochloride (0.27 g, 1.4 mmol) in HOAc (20 mL) Purification using silica gel, eluting with 19:1 CH2Cl2 /MeOH, afforded a solid that was converted to an HCl salt and recrystallized from EtOAc/MeOH to give 135 as a white solid (m.p. 219-220° C.).

Provenance & Evidence