Trifluoroacetic acid → HCID 86755499, compound

HRID 2287889Notes

Reaction equation

HRID 2287889 reaction equation
C(O[C:6]([N:8](C)[NH:9][C:10](=[O:12])[CH3:11])=O)(C)(C)C.[F:14][C:15]([F:20])([F:19])[C:16]([OH:18])=[O:17]>C(Cl)Cl>[F:14][C:15]([F:20])([F:19])[C:16]([OH:18])=[O:17].[CH3:6][NH:8][NH:9][C:10](=[O:12])[CH3:11]

Participants

4

Reactant 2

HCID 6422Trifluoroacetic acidHCID 45158400HCID 45158400, compound

Product 1

HCID 86755499HCID 86755499, compoundYield 100%

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

To a solution of N'-acetyl-N-methylhydrazinecarboxylic acid tert-butyl ester (0.3 g, 1.59 mmol) in methylene chloride (2 ml) was added trifluoroacetic acid (2 ml) and the mixture was stirred for 60 min. The mixture was concentrated in vacuo and stripped three times with methylene chloride to give 0.32 g (100%) of acetic acid N'-methylhydrazide trifluoroacetic acid as a thin oil.

Workup

  1. concentrationThe mixture was concentrated in vacuo

Sources & evidence

ORD record
ord-6a3e172edeef421d83dc351a19a4dc11
Source dataset
uspto-grants-2000_07
Patent number
US06083908

Reaction notes

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