N,N'-Dimethylurea → HCID 18702574, compound

HRID 2287919Notes

Reaction equation

HRID 2287919 reaction equation
[CH3:1][NH:2][C:3]([NH:5][CH3:6])=[O:4].C(N(CC)CC)C.[C:14](Cl)(=[O:26])[CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH3:25]>C1(C)C=CC=CC=1>[C:14]([N:2]([CH3:1])[C:3]([NH:5][CH3:6])=[O:4])(=[O:26])[CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH3:25]

Participants

5

Reactant 3

HCID 7293N,N'-DimethylureaHCID 8166Dodecanoyl chlorideHCID 8471Triethylamine

Product 1

HCID 18702574HCID 18702574, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

To a solution of 1,3-dimethylurea in toluene with an appropriate base (e.g., triethylamine) is added an equimolar amount of lauroyl chloride. This is stirred overnight, filtered and concentrated to give the above product.

Workup

  1. filtrationfiltered
  2. concentrationconcentrated
  3. customto give the above product

Sources & evidence

ORD record
ord-e8af2f23633e4ef9bf77a4ad9b0be2cd
Source dataset
uspto-grants-2000_07
Patent number
US06086905

Reaction notes

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