Hydrochloric Acid → HCID 86584236, compound

Participants

Reaction Steps

A solution of (2R)-2-(3,4-dichlorobenzyl)-1-[3,5-bis(trifluoromethyl)benzoyl]-4-(2-hydroxyethyl)piperazine (50 mg) in ethyl acetate (3 ml) was treated with 4N hydrogen chloride in ethyl acetate solution (0.2 ml) and the resulting mixture was concentrated in vacuo to give (2R)-2-(3,4-dichlorobenzyl)-1-[3,5-bis(trifluoromethyl)benzoyl]-4-(2-hydroxyethyl)piperazine hydrochloride (45 mg) as a powder.

Provenance & Evidence