反应详情

8.35 g (50 mMol) of 2-Methyl-5-methylamino-6-nitro-pyridine (Heterocycles 38, 529 (1994)) were dissolved in 300 l ethyl acetate and hydrogenated with 1.5 g Raney nickel for 3.5 hours at room temperature. Then the catalyst was filtered off and the filtrate was evaporated down. After crystallisation of the resulting residue from petroleum ether, 5.75 g (84% of theory) were obtained as olive-green crystals. C7H11N3 (137.20) Melting point: 112-113° C.

1. filtrationThen the catalyst was filtered off
2. customthe filtrate was evaporated down
3. customAfter crystallisation of the resulting residue from petroleum ether
4. custom5.75 g (84% of theory) were obtained as olive-green crystals