HRID2288480

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID14798

Sodium Hydroxide

HNaO

结构：CCOC(=O)CCN(C(=O)c1ccc2c(c1)nc(SCc1ccc(C(=N)N)cc1)n2C)c1ccccc1.Cl

HCID18412612

未命名化合物

PRODUCTS

生成物

结构：Cl.Cn1c(SCc2ccc(C(=N)N)cc2)nc2cc(C(=O)N(CCC(=O)O)c3ccccc3)ccc21

HCID18412732

未命名化合物

收率 57%

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID887

Methanol

CH4O

PROCEDURE

实验过程

Prepared analogously to Example 10 from 1-methyl-2-[(4-amidinophenyl)methylthio]-benzimidazol-5-yl-carboxylic acid-N-phenyl-N-(2-ethoxycarbonylethyl)-amide-hydrochloride and sodium hydroxide solution. Yield: 57% of theory, C26H25N5O3S (487.58) Rf value: 0.23 (Reversed Phase silica gel RP-8; Methanol/5% saline solution=6:4) ##EQU93##