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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2288481Generated: October 30, 2026

Hydrochloric Acid → HCID 18412720, compound

https://huagongshe.com/reaction/2288481

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantEthanolHCID 702—
ReactantAmmonium CarbonateHCID 517111—
ReactantHCID 18412640HCID 18412640—
SolventDichloromethane ethanolHCID 21584144—
ProductHCID 18412720HCID 1841272081%

Reaction Steps

Prepared analogously to Example 25d from 1-methyl-2-[N-(4-cyanophenyl)-aminomethyl]-benzimidazol-5-yl-carboxylic acid-N-propargyl-N-(2-ethoxycarbonylethyl)-amide, ethanolic hydrochloric acid, ethanol and ammonium carbonate. Yield: 81% of theory, C25H28N6O3 (460.6) Rf value: 0.094 (silica gel; dichloromethane/ethanol=4:1) ##EQU94##

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06087380
Source datasetuspto-grants-2000_07
ORD IDord-825d21a1ccca40e38d8ecccc749af708
Source noteuspto-grants-2000_07