HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → HCID 18412381, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | HCID 18412599 | HCID 18412599 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 18412381 | HCID 18412381 | 11% |
Reaction Steps
Prepared analogously to Example 26 from 1-methyl-2-[N-(2-amidino-pyrazin-5-yl)-aminomethyl]-benzimidazol-5-yl-carboxylic acid-N-(2-pyridyl)-N-(2-ethoxycarbonylethyl)-amide-hydrochloride and sodium hydroxide solution. Yield: 11% of theory, C23H23N9O3 (473.5) Rf value: 0.55 (Reversed Phase silica gel RP-8; 5% saline solution/methanol=6:4) ##EQU139##
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06087380 |
| Source dataset | uspto-grants-2000_07 |
| ORD ID | ord-3cf432cba4bf483e8ddc4b78d401b625 |
| Source note | uspto-grants-2000_07 |