HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hexyl chloroformate → hexyl (NZ)-N-[amino-[4-[2-[1-methyl-5-[phenyl-[2-(2H-tetrazol-5-yl)ethyl]carbamoyl]benzimidazol-2-yl]ethyl]phenyl]methylidene]carbamate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hexyl chloroformate | HCID 22466 | — |
| Reactant | HCID 178480190 | HCID 178480190 | — |
| Solvent | Dichloromethane methanol | HCID 21226129 | — |
| Product | hexyl (NZ)-N-[amino-[4-[2-[1-methyl-5-[phenyl-[2-(2H-tetrazol-5-yl)ethyl]carbamoyl]benzimidazol-2-yl]ethyl]phenyl]methylidene]carbamate | HCID 178445089 | — |
Reaction Steps
Prepared analogously to Example 90 from 1-methyl-2-[2-(4-amidinophenyl)-ethyl]-benzimidazol-5-yl-carboxylic acid-N-phenyl-N-[2-(1H-tetrazol-5-yl)-ethyl]-amide and n-hexyl chloroformate. Yield: % of theory, C34H39N9O3 (621.7) Rf value: (silica gel; dichloromethane/methanol=4:1)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06087380 |
| Source dataset | uspto-grants-2000_07 |
| ORD ID | ord-6a7f2fa6eedd4f6f96e6d8c077f95ef7 |
| Source note | uspto-grants-2000_07 |