HCID 54171432, compound → HCID 18699630, compound

HRID 2288588Notes

Reaction equation

HRID 2288588 reaction equation
[S:1]1[CH:5]=[CH:4][C:3]([CH2:6][CH2:7][NH:8][C:9]([CH:11]2[CH2:16][CH2:15][N:14]([CH3:17])[CH2:13][CH2:12]2)=O)=[CH:2]1>C1(C)C=CC=CC=1>[CH3:17][N:14]1[CH2:15][CH2:16][CH:11]([C:9]2[C:2]3[S:1][CH:5]=[CH:4][C:3]=3[CH2:6][CH2:7][N:8]=2)[CH2:12][CH2:13]1

Participants

3

Reactant 1

HCID 54171432HCID 54171432, compound

Product 1

HCID 18699630HCID 18699630, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

1-Methylpiperidine-4-carboxylic acid (2-thiophen-3-yl-ethyl)-amide (1.2 g) POCl3 (1.22 ml) were reacted in toluene (50 ml) exactly as described in example 4. 1.1 g of [7-(1-Methylpiperidin-4-yl)-4,5,-dihydrothieno[2,3-c]pyridine was isolated identified by NMR and MS: M+=234.

Sources & evidence

ORD record
ord-a5c4a8f5a70a413ca0b2ff95b28ac6d6
Source dataset
uspto-grants-2000_07
Patent number
US06090797

Reaction notes

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