Hydrochloric Acid → HCID 1484508, compound

HRID 2288657Notes

Reaction equation

HRID 2288657 reaction equation
[Cl:1][C:2]1[CH:9]=[CH:8][C:5]([CH2:6][NH2:7])=[CH:4][CH:3]=1.[O-:10][C:11]#[N:12].[Na+].Cl>O>[Cl:1][C:2]1[CH:9]=[CH:8][C:5]([CH2:6][NH:7][C:11]([NH2:12])=[O:10])=[CH:4][CH:3]=1

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 660364-ChlorobenzylamineHCID 517096Sodium Cyanate2×

Product 1

HCID 1484508HCID 1484508, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

100 ml of 95% 4-chlorobenzylamine and 51.53 g of sodium cyanate in 1 liter of water were treated below 25° C. with 194 ml of 4N HCl. Further sodium cyanate (5.15 g) was added and the pH adjusted to 7.3. After 3 days the solid was collected, washed with water and dried to give the title compound (131.1 g) as a white solid mp 186-9° C.

Workup

  1. customAfter 3 days the solid was collected
  2. washwashed with water
  3. customdried

Sources & evidence

ORD record
ord-4b52fe24dea642b68fb4285a065b40fb
Source dataset
uspto-grants-2000_07
Patent number
US06090816

Reaction notes

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