Ethanethiol → HCID 15888339, compound

HRID 2288915Notes

Reaction equation

HRID 2288915 reaction equation
C[O:2][C:3]1[CH:4]=[CH:5][C:6]2[C:10]([C:11]([C:13]3[CH:18]=[CH:17][C:16]([O:19][CH2:20][CH2:21][O:22][C:23]([CH:25]4[CH2:30][CH2:29][CH2:28][CH2:27][CH2:26]4)=[O:24])=[CH:15][CH:14]=3)=[O:12])=[C:9]([C:31]3[CH:36]=[CH:35][C:34]([O:37]C)=[CH:33][CH:32]=3)[S:8][C:7]=2[CH:39]=1.C(S)C.[Cl-].[Al+3].[Cl-].[Cl-]>>[OH:2][C:3]1[CH:4]=[CH:5][C:6]2[C:10]([C:11]([C:13]3[CH:14]=[CH:15][C:16]([O:19][CH2:20][CH2:21][O:22][C:23]([CH:25]4[CH2:26][CH2:27][CH2:28][CH2:29][CH2:30]4)=[O:24])=[CH:17][CH:18]=3)=[O:12])=[C:9]([C:31]3[CH:32]=[CH:33][C:34]([OH:37])=[CH:35][CH:36]=3)[S:8][C:7]=2[CH:39]=1

Participants

4

Reactant 3

HCID 6343EthanethiolHCID 6451240Aluminum(III) ChlorideHCID 15888338HCID 15888338, compound

Product 1

HCID 15888339HCID 15888339, compoundYield 48%

Procedure

[6-Methoxy-2-(4-methoxyphenyl)benzo[b]thiophen-3-yl][4-(cyclohexanoyloxyethoxy)phenyl]methanone (1.25 g, 2.3 mmol) was converted to the title compound by the procedure of Example 3 using 400 mg (7.0 mmol) of ethanethiol and 920 mg (7.00 mmol) of aluminum chloride (0.92 g, 7.00 mmol).

Sources & evidence

ORD record
ord-2ecab449afb2466a8716316c03f39616
Source dataset
uspto-grants-2000_07
Patent number
US06090843

Reaction notes

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