Ethanethiol → [6-Hydroxy-2-(4-Hydroxyphenyl)benzo[b]thiophen-3-yl][4-(Trimethylacetoxymethoxy)phenyl]methanone

Participants

Role	Name	HCID	Charge
Reactant	Ethanethiol	HCID 6343	—
Reactant	Aluminum(III) Chloride	HCID 6451240	—
Reactant	HCID 21701999	HCID 21701999	—
Product	[6-Hydroxy-2-(4-Hydroxyphenyl)benzo[b]thiophen-3-yl][4-(Trimethylacetoxymethoxy)phenyl]methanone	HCID 21702002	69%

Reaction Steps

[6-Methoxy-2-(4-Methoxyphenyl)benzo[b]thiophen-3-yl][4-(Trimethylacetoxymethoxy)phenyl]methanone (760 mg, 1.5 mmol) was converted to the title compound by the procedure of Example 3 using 300 mg (4.5 mmol) of ethanethiol and 600 mg (4.5 mmol) of aluminum chloride.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US06090843
Source dataset	uspto-grants-2000_07
ORD ID	ord-6c545075d6b548ebb344aca7561870de
Source note	uspto-grants-2000_07