tert-Butylacetic acid → 1-(2,4-Dihydroxy-3-propylphenyl)-3,3-dimethylbutan-1-one

HRID 2289114Notes

Reaction equation

HRID 2289114 reaction equation
[CH3:1][C:2]([CH3:8])([CH3:7])[CH2:3][C:4](O)=[O:5].[CH2:9]([C:12]1[C:18]([OH:19])=[CH:17][CH:16]=[CH:15][C:13]=1[OH:14])[CH2:10][CH3:11]>OS(C(F)(F)F)(=O)=O>[OH:14][C:13]1[CH:15]=[CH:16][C:17]([C:4](=[O:5])[CH2:3][C:2]([CH3:8])([CH3:7])[CH3:1])=[C:18]([OH:19])[C:12]=1[CH2:9][CH2:10][CH3:11]

Participants

4

Reactant 2

HCID 14057tert-Butylacetic acidHCID 2620601,3-Benzenediol, propyl-

Product 1

HCID 219109861-(2,4-Dihydroxy-3-propylphenyl)-3,3-dimethylbutan-1-one

Reagents, catalysts & solvents 1

HCID 62406Trifluoromethanesulfonic acidSolvent

Procedure

Using the procedure in Example 51, step 1, 3,3-dimethylbutyric acid and 2-(n-propyl)resorcinol were condensed in triflic acid to form 1,3-dihydroxy-4-(3,3-dimethylbutyryl)-2-(n-propyl)benzene

Sources & evidence

ORD record
ord-6d9e32a98ef04d558ead828fe2d2ea4a
Source dataset
uspto-grants-2000_07
Patent number
US06090836

Reaction notes

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