Isopropanol → Diisopropyl tartrate

Participants

Reaction Steps

Diisopropyl (R,R)-tartrate was prepared according to the procedure described in J. Am. Chem. Soc., 1981, 6237. 400 g of (R,R)-tartaric acid, 400 mL of isopropanol and 5 g of p-TsOH were heated in refluxing benzene to afford, following distillation, 201 g (55%) of the above-titled compound: bp.=103-105° C. (2 torr) (lit. 152° C. (12 torr)).

Provenance & Evidence