反应详情

The derivative 3,3-dimethyl-benzisoselenazoline BXT-51056 (212 mg; 1 mmole) was dissolved at room temperature in methanol (5 ml) with stirring. After addition of 5% hydrogen peroxide (600 μl; 1.05 mmole), stirring was continued for 15 min. The solvent was evaporated off under reduced pressure. The residue was taken up in 25 ml of dichloromethane and washed with 3×3 ml of a saturated NaCl solution, dried over Na2SO4 then filtered. After evaporation of the solvent under reduced pressure, the desired product was obtained in the form of yellowish crystals.

1. stirringstirring
2. customThe solvent was evaporated off under reduced pressure
3. washwashed with 3×3 ml of a saturated NaCl solution
4. dry with materialdried over Na2SO4
5. filtrationthen filtered
6. customAfter evaporation of the solvent under reduced pressure