Tryptamine → Tetrahydro-beta-carboline

HRID 2289494Notes

Reaction equation

HRID 2289494 reaction equation
[NH2:1][CH2:2][CH2:3][C:4]1[C:12]2[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=2)[NH:6][CH:5]=1.S(N1CC(C)(C)N(C)C1)([C:16]1C=CC(C)=CC=1)(=O)=O>>[CH2:16]1[C:5]2[NH:6][C:7]3[C:12](=[CH:11][CH:10]=[CH:9][CH:8]=3)[C:4]=2[CH2:3][CH2:2][NH:1]1

Participants

3

Reactant 2

HCID 1150TryptamineHCID 1265881-(p-Tosyl)-3,4,4-trimethylimidazolidine

Product 1

HCID 107838Tetrahydro-beta-carboline

Procedure

treating the 3-(2-amino)ethyl indole with 1-tosyl-3,4,4-trimethylimidazolidine to produce a tetrahydro-β-carboline derivative; and

Sources & evidence

ORD record
ord-212655321c4c41af87ff131b4c524c39
Source dataset
uspto-grants-2000_07
Patent number
US06093723

Reaction notes

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