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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 228967Generated: October 29, 2026

Hydrochloride methanol → HCID 23078411, compound

https://huagongshe.com/reaction/228967

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloride methanolHCID 21893726—
ReactantHCID 23078262HCID 23078262—
ProductHCID 23078411HCID 2307841159%

Reaction Steps

A hydrochloric acid/methanol solution (30 ml) was added to 6-methoxy-4-(2-methyl-quinolin-3-yloxy)-7-(2-morpholin-4-yl-ethoxy)-quinoline (compound 365) (748 mg), and the mixture was stirred at room temperature for one hr. The solvent was removed by distillation under the reduced pressure to give the title compound (900 mg, yield 59%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07560558B2
Source datasetuspto-grants-2009_07
ORD IDord-a61a77b601f241fe85d7f156fbfaa5c4
Source noteuspto-grants-2009_07