HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2289810Generated: November 1, 2026
Hydrochloric Acid → Ethyl 1-aminocyclobutane-1-carboxylate hydrochloride
https://huagongshe.com/reaction/2289810
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 1-Aminocyclobutanecarboxylic acid | HCID 89643 | — |
| Reactant | 1-Amino-cyclobutanecarboxylic acid ethyl ester | HCID 11457751 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | Ethyl 1-aminocyclobutane-1-carboxylate hydrochloride | HCID 16217503 | — |
Reaction Steps
Ethyl 1-aminocyclobutanecarboxylate ##STR153## A solution 1-aminocyclobutanecarboxylic acid (500 mg, 4.34 mmol) in EtOH (10 mL) was saturated with HCl gas, and the mixture was stirred at 23° C. for 4 d. The solvents were vaporated in vacuo, azeotroping with PhMe and CH2Cl2, to give ethyl 1-aminocyclobutanecarboxylate hydrochloride (754 mg, 4.20 mmol) as an off-white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US06093731 |
|---|
| Source dataset | uspto-grants-2000_07 |
|---|
| ORD ID | ord-f3f57362f4b649779e3d4e9ee339f4ce |
|---|
| Source note | uspto-grants-2000_07 |
|---|
