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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2289872Generated: October 31, 2026

Sarcosine → Creatine

https://huagongshe.com/reaction/2289872

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSarcosineHCID 1088—
ReactantCarbamimidic acid, methyl ester, hydrochloride (1:1)HCID 3083899—
ProductCreatineHCID 586—

Reaction Steps

The reaction of sarcosine with O-methylisourea hydrochloride, described by E. Schutte in Hoppe-Seylers Z. Physiol. Chemie 279 (1943) 52-59, affords creatine in a yield of only 21%.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06093848
Source datasetuspto-grants-2000_07
ORD IDord-25f04663b0a8469da830c9806ac11aa1
Source noteuspto-grants-2000_07