反应详情

A suspension of the title compound of Example 53 (0.300 g) and 10% Pd/C (0.03 g) in 25 mL of 3:1 CH2Cl2 /MeOH is hydrogenated at atmospheric pressure overnight. The reaction is filtered through celite. The filtrate is condensed. The crude product is recrystallized from EtOAc/hexanes to yield 0.200 g of the desired product as a pale-yellow solid.

1. customis hydrogenated at atmospheric pressure overnight
2. filtrationThe reaction is filtered through celite
3. customcondensed
4. customThe crude product is recrystallized from EtOAc/hexanes