HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 178522909, compound → HCID 178522910, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 178522909 | HCID 178522909 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Dichloromethane methanol | HCID 21226129 | — |
| Product | HCID 178522910 | HCID 178522910 | 66% |
Reaction Steps
A suspension of the title compound of Example 53 (0.300 g) and 10% Pd/C (0.03 g) in 25 mL of 3:1 CH2Cl2 /MeOH is hydrogenated at atmospheric pressure overnight. The reaction is filtered through celite. The filtrate is condensed. The crude product is recrystallized from EtOAc/hexanes to yield 0.200 g of the desired product as a pale-yellow solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06093732 |
| Source dataset | uspto-grants-2000_07 |
| ORD ID | ord-d72ae011d3fd48b2a4a5841b3ebf6c96 |
| Source note | uspto-grants-2000_07 |