HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Nitro-1,3-dihydroisobenzofuran → 4-Amino-1,3-dihydroisobenzofuran
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Nitro-1,3-dihydroisobenzofuran | HCID 13472251 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Product | 4-Amino-1,3-dihydroisobenzofuran | HCID 13472252 | — |
Reaction Steps
Nitration of the 1,3-dihydro-iso-benzofuran derivatives of Formula 17 provides the 1,3-dihydro-4-nitro-iso-benzofuran compounds of Formula 18. The nitro compounds of Formula 18 are reduced with hydrogen on a suitable catalyst, such as palladium, to give the 1,3-dihydro-4-amino-iso-benzofuran compounds of Formula 19.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06093838 |
| Source dataset | uspto-grants-2000_07 |
| ORD ID | ord-7e05cede79f142458dc3fb56cac26c49 |
| Source note | uspto-grants-2000_07 |