反应详情

In 70 ml of tetrahydrofuran were dissolved 9.0 g of 4-ethoxycarbonylphenylhydrazine and 9.7 g of 1,3-diphenylcarbodiimide and after stirring the solution for one hour under ice-cooling, tetrahydrofuran was distilled off under reduced pressure. Then, when 70 ml of benzene and 70 ml of n-hexane were added to the residue thus formed, crystals deposited. By collecting the crystals thus deposited by filtration, 15.4 g of 1,2-diphenyl-3-(4-ethoxycarbonylphenylamino)guanidine was obtained.

1. temperaturecooling
2. distillationtetrahydrofuran was distilled off under reduced pressure
3. additionThen, when 70 ml of benzene and 70 ml of n-hexane were added to the residue
4. customthus formed
5. customBy collecting the crystals
6. filtrationthus deposited by filtration