反应详情

12.5 gm (36.9 mmols) of 5-methyl-6-[3'-nitro-4'-benzylamino-phenyl]-4,5-dihydro-3(2H)-pyridazinone were added to a mixture of 20 ml of 99% hydrazine hydrate and 350 ml of ethanol, and then 10 gm of Raney nickel were added. After 24 hours' stirring at room temperature, the solid components were suction-filtered off, dissolved in dimethyl formamide, the catalyst was filtered off, and the filtrate was evaporated. The crystalline residue thus obtained was digested with ethanol, washed with ether and dried.

1. filtrationthe solid components were suction-filtered off
2. dissolutiondissolved in dimethyl formamide
3. filtrationthe catalyst was filtered off
4. customthe filtrate was evaporated
5. customThe crystalline residue thus obtained
6. washwashed with ether
7. customdried