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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2290242Generated: November 2, 2026

1-Acetylpiperazine → HCID 45262550, compound

https://huagongshe.com/reaction/2290242

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-AcetylpiperazineHCID 83795—
Reactant7-Chloro-6-fluoro-4-oxo-1-phenyl-1,4-dihydro-1,8-naphthyridine-3-carboxylic acidHCID 13715315—
ProductHCID 45262550HCID 45262550—

Reaction Steps

In the described fashion as Example 1(f) the above ester (III) reacting with N-acetylpiperazine can give the desired 1-p-fluorophenyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-1,8-naphthyridine-3-carboxylic acid (I) ##STR28## and its hydrochloride salt.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04616019
Source datasetuspto-grants-1986_10
ORD IDord-800c4fa06f9e425a89e4444da0b0e21d
Source noteuspto-grants-1986_10