Water → HCID 13469415, Verbindung

HRID 2290280Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2290280
C([O:4][CH:5]([CH3:23])[C:6]([NH:8][C:9]1[CH:14]=[CH:13][C:12]([C:15]2[CH:16]([CH3:22])[NH:17][C:18](=[O:21])[NH:19][N:20]=2)=[CH:11][CH:10]=1)=[O:7])(=O)C.[OH-].[Na+].O>CO>[C:6]([NH:8][C:9]1[CH:10]=[CH:11][C:12]([C:15]2[CH:16]([CH3:22])[NH:17][C:18](=[O:21])[NH:19][N:20]=2)=[CH:13][CH:14]=1)(=[O:7])[CH:5]([CH3:23])[OH:4]

Komponenten

5

Edukt 3

HCID 962WaterHCID 14798Sodium HydroxideHCID 202321356-[4-(2-acetoxypropionylamino)phenyl]-5-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one

Produkt 1

HCID 13469415HCID 13469415, VerbindungAusbeute 74,8 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 887MethanolLösungsmittel

Versuchsvorschrift

To a stirred solution of 6-[4-(2-acetoxypropionylamino)phenyl]-5-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one (0.94 g) in methanol (6 ml) was added dropwise 1N sodium hydroxide (3 ml) under ice cooling. The mixture was stirred for 15 minutes after adding water. The resulting precipitates were collected by filtration, washed with water and dried to give 0.61 g of 6-(4-lactoylaminophenyl)-5-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one.

Aufarbeitung

  1. customThe resulting precipitates
  2. filtrationwere collected by filtration
  3. washwashed with water
  4. customdried

Quellen und Nachweise

ORD-Eintrag
ord-ee28d75828104336b22e56193178c061
Quelldatensatz
uspto-grants-1986_10
Patentnummer
US04616015

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