Sodium Hydroxide → HCID 20232224, compound

HRID 2290292Notes

Reaction equation

HRID 2290292 reaction equation
[BH4-].[Na+].[CH3:3][O:4][C:5]1[CH:6]=[CH:7][C:8]2[CH2:14][CH2:13][C:12]3[CH:15]=[CH:16][CH:17]=[CH:18][C:11]=3[C:10](=[O:19])[C:9]=2[CH:20]=1.[OH-].[Na+]>C(O)C>[CH3:3][O:4][C:5]1[CH:6]=[CH:7][C:8]2[CH2:14][CH2:13][C:12]3[CH:15]=[CH:16][CH:17]=[CH:18][C:11]=3[CH:10]([OH:19])[C:9]=2[CH:20]=1

Participants

5

Reactant 3

HCID 14798Sodium HydroxideHCID 4311764Sodium borohydrideHCID 202322663-Methoxy-10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-one

Product 1

HCID 20232224HCID 20232224, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

In a manner similar to that described in the preceding examples, 0.5 gram (13 millimoles) of sodium borohydride was added to a solution of 1 gram (43 millimoles) of 10,11-dihydro-3-methoxy-5H-dibenzo[a,d]cyclohepten-5-one in 20 milliliters of ethanol with an added drop of 40 percent sodium hydroxide solution and the mixture heated overnight to obtain 10,11-dihydro-3-methoxy-5H-dibenzo[a,d]cyclohepten-5-ol (5-hydroxy intermediate compound) in the reaction mixture.

Workup

  1. temperaturethe mixture heated overnight

Sources & evidence

ORD record
ord-aeb4b3cf5d7c4defad93e85ee09fb93a
Source dataset
uspto-grants-1986_10
Patent number
US04616023

Reaction notes

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