m-Chloroperbenzoic acid → HCID 20232107, compound

HRID 2290337Notes

Reaction equation

HRID 2290337 reaction equation
ClC1C=CC=C(C(OO)=[O:9])C=1.[CH3:12][C:13]1[N:14]=[C:15]([S:25][CH3:26])[N:16]=[N:17][C:18]=1[C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1>C(Cl)(Cl)Cl>[CH3:12][C:13]1[N:14]=[C:15]([S:25]([CH3:26])=[O:9])[N:16]=[N:17][C:18]=1[C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1

Participants

4

Reactant 2

HCID 70297m-Chloroperbenzoic acidHCID 15586342HCID 15586342, compound

Product 1

HCID 20232107HCID 20232107, compoundYield 88.5%

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

m-Chloroperbenzoic acid (20 g) was added to a stirred solution of 5-methyl-3-methylthio-6-phenyl-1,2,4-triazine (20 g) in chloroform (600 ml) under ice cooling, and the mixture was stirred for 30 minutes at room temperature. The reaction mixture was washed with a saturated aqueous solution of sodium bicarbonate, dried over sodium sulfate, and then concentrated. The resulting residue was crystallized with diethyl ether, and the crystals were collected by filtration, washed with diethyl ether and dried to give 5-methyl-3-methylsulfinyl-6-phenyl-1,2,4-triazine (19.0 g).

Workup

  1. washThe reaction mixture was washed with a saturated aqueous solution of sodium bicarbonate
  2. dry with materialdried over sodium sulfate
  3. concentrationconcentrated
  4. customThe resulting residue was crystallized with diethyl ether
  5. filtrationthe crystals were collected by filtration
  6. washwashed with diethyl ether
  7. customdried

Sources & evidence

ORD record
ord-a4b4184592cf4e1da36ce71f8b34d588
Source dataset
uspto-grants-1986_10
Patent number
US04616014

Reaction notes

Loading…