Sodium borohydride → HCID 15586362, compound

HRID 2290355Notes

Reaction equation

HRID 2290355 reaction equation
[BH4-].[Na+].[C:3]([NH:11][NH:12][C:13]1[N:14]=[N:15][C:16]([C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=2)=[C:17]([CH3:19])[N:18]=1)(=[O:10])[C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1>C(OC(C)C)(C)C>[C:3]([NH:11][NH:12][C:13]1[NH:14][N:15]=[C:16]([C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=2)[CH:17]([CH3:19])[N:18]=1)(=[O:10])[C:4]1[CH:5]=[CH:6][CH:7]=[CH:8][CH:9]=1

Participants

4

Reactant 2

HCID 4311764Sodium borohydrideHCID 20232088HCID 20232088, compound

Product 1

HCID 15586362HCID 15586362, compoundYield 50.7%

Reagents, catalysts & solvents 1

HCID 7914Diisopropyl EtherSolvent

Procedure

Sodium borohydride (1.98 g) and 3-(2-benzoylhydrazino)-5-methyl-6-phenyl-1,2,4-triazine (3.45 g) was reacted in a similar manner to that of Example 2-(2). The reaction mixture was diluted with diisopropyl ether and the resultant precipitates were collected, washed successively with water, methanol and diisopropyl ether, and recrystallized from a mixture of ethanol, chloroform and water to give colorless crystals of 3-(2-benzoylhydrazino)-5-methyl-6-phenyl-2,5-dihydro-1,2,4-triazine (1.76 g), m.p. 217.5°-218° C. (decomp.).

Workup

  1. customthe resultant precipitates
  2. customwere collected
  3. washwashed successively with water, methanol and diisopropyl ether
  4. customrecrystallized from a mixture of ethanol, chloroform and water

Sources & evidence

ORD record
ord-629ead289a6e4ebab239106b8e7cd877
Source dataset
uspto-grants-1986_10
Patent number
US04616014

Reaction notes

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