Methyl Isocyanate → HCID 20232058, compound

HRID 2290356Notes

Reaction equation

HRID 2290356 reaction equation
[CH3:1][N:2]=[C:3]=[O:4].[NH:5]([C:7]1[N:8]=[N:9][C:10]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)=[C:11]([CH3:13])[N:12]=1)[NH2:6]>C(Cl)Cl.C(OC(C)C)(C)C>[CH3:13][C:11]1[N:12]=[C:7]([NH:5][NH:6][C:3]([NH:2][CH3:1])=[O:4])[N:8]=[N:9][C:10]=1[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1

Participants

5

Reactant 2

HCID 12228Methyl IsocyanateHCID 15586409HCID 15586409, compound

Product 1

HCID 20232058HCID 20232058, compoundYield 98.7%

Reagents, catalysts & solvents 2

HCID 6344DichloromethaneSolvent2×HCID 7914Diisopropyl EtherSolvent

Procedure

A solution of methyl isocyanate (0.92 g) in methylene chloride (3 ml) was added dropwise to a stirred solution of 3-hydrazino-5-methyl-6-phenyl-1,2,4-triazine (3 g) in methylene chloride (20 ml) at room temperature. The reaction mixture was diluted with diisopropyl ether (30 ml). The resultant precipitates were collected by filtration to give a solid of 5-methyl-3-(4-methylsemicarbazido)-6-phenyl-1,2,4-triazine (3.8 g).

Workup

  1. customThe resultant precipitates
  2. filtrationwere collected by filtration

Sources & evidence

ORD record
ord-b2418dbf094841a0b455856c0471b5d2
Source dataset
uspto-grants-1986_10
Patent number
US04616014

Reaction notes

Loading…