Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Thiosemicarbazide | HCID 2723789 | — |
| Reactant | 1,2-Propanedione, 1-phenyl-, 2-oxime | HCID 6399024 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | HCID 135544474 | HCID 135544474 | 86.6% |
Reaction Steps
A mixture of 2-hydroxyiminopropiophenone (150 g) and thiosemicarbazine (90 g) in acetic acid (500 ml) was heated at 60° C. for 60 hours with stirring. After cooling, water was added to the reaction mixture. The resultant precipitates were collected by filtration, washed successively with water, methanol and diisopropyl ether, and dried to give 2-hydroxyiminopropiophenone thiosemicarbazone (188.2 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US04616014 |
|---|
| Source dataset | uspto-grants-1986_10 |
|---|
| ORD ID | ord-562e054d1962401c9387696941169c96 |
|---|
| Source note | uspto-grants-1986_10 |
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