Propylene Oxide → HCID 13135958, compound

Participants

Reaction Steps

A mixture of 13.1 g. (50 mmole) n-butyl 4-(piperazin-1-yl)-benzoate, 2.9 g. (50 mmole) propylene oxide and 6 ml. methanol is stirred for 24 hours at 20° C. The solvent is then evaporated off and the residue is triturated with ligroin to give a yield of 78% of theory of the desired product; m.p. 85°-86° C.

Provenance & Evidence