Methanol → 6-Methoxy-N-(propan-2-yl)pyridin-2-amine

Participants

Reaction Steps

In the same reacting apparatus as in Example 1, 20 g of 2-bromo-6-isopropylaminopyridine, 70 ml of methanol and 14 g of potassium hydroxide were charged and they were subjected to reacting each other at 160° C. for 4 hours. After completion of the reaction, the similar experimental procedure as in Example 3 was carried out to give 7.3 g of 2-methoxy-6-isopropylaminopyridine of b.p. 127°-128° C./20 mmHg.

Provenance & Evidence