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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2290642Generated: October 31, 2026

Piperidine-2-methylamine → Flecainide

https://huagongshe.com/reaction/2290642

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPiperidine-2-methylamineHCID 90865—
ReactantBenzoyl chloride, 2,5-bis(2,2,2-trifluoroethoxy)-HCID 11427683—
ProductFlecainideHCID 3356—

Reaction Steps

contacting the resultant 2,5-bis(2,2,2-trifluoroethoxy)benzoic acid chloride with 2-aminomethylpiperidine, whereby there is formed 2,5-bis(2,2,2-trifluoroethoxy)-N-(2-piperidylmethyl)benzamide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04617396
Source datasetuspto-grants-1986_10
ORD IDord-60e09ac26b314c34948c38d384f34d22
Source noteuspto-grants-1986_10