Potassium Carbonate → Tranylcypromine

HRID 2290646Notes

Reaction equation

HRID 2290646 reaction equation
C(=O)([O-])[O-].[K+].[K+].C[C:8]1[C:14](=O)[C:13]2N3[C@@:20](OC)([C@H:21](COC(N)=O)[C:12]=2[C:10](=O)[C:9]=1OC)[C@H:19]1[NH:29][C@H]1C3>>[C:12]1([CH:21]2[CH2:20][CH:19]2[NH2:29])[CH:10]=[CH:9][CH:8]=[CH:14][CH:13]=1

Participants

3

Reactant 2

HCID 11430Potassium CarbonateHCID 19972Mitomycin A

Product 1

HCID 5530Tranylcypromine

Procedure

This compound was prepared by the procedure described in Example 1, except that the potassium carbonate was omitted. From 125 mg. of mitomycin A and 85 mg. of 2-phenylcyclopropylamine was obtained 70 mg. (63%) of the desired product decomposing at temperatures above 250° C. and providing the following analysis:

Workup

  1. customThis compound was prepared by the procedure

Sources & evidence

ORD record
ord-7a1b09be4f1146bf9be00048874f0051
Source dataset
uspto-grants-1986_10
Patent number
US04617389

Reaction notes

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