Ethanamine, 2-fluoro-, hydrochloride → HCID 20231566, compound

Participants

Reaction Steps

This compound was prepared by the procedure described in Example 1, except that the 2-fluoroethylamine hydrochloride (220 mg.) was neutralized with sodium methoxide (119 mg.) in 2 ml. of methanol at 5° C. before the mitomycin A (77 mg.) was added, and potassium carbonate was not used. A 62 mg. (74%) yield of the desired product was obtained, having no melting point below 340° C. and providing the following analysis:

Provenance & Evidence