Potassium Carbonate → P-Anisidine

HRID 2290650Notes

Reaction equation

C(=O)([O-])[O-].[K+].[K+].C[C:8]1[C:14](=O)[C:13]2[N:16]3[C@@](OC)([C@H](COC(N)=O)[C:12]=2[C:10](=O)[C:9]=1[O:30][CH3:31])[C@H]1N[C@H]1C3>>[CH3:31][O:30][C:9]1[CH:10]=[CH:12][C:13]([NH2:16])=[CH:14][CH:8]=1

Participants

Reactant 2

HCID 11430Potassium Carbonate

HCID 19972Mitomycin A

Product 1

HCID 7732P-Anisidine

Procedure

This compound was prepared by the procedure described in Example 1, except that the potassium carbonate was omitted. From 77 mg. of mitomycin A and 27 mg. of 4-methoxyaniline was obtained 70 mg. (74% yield) of the desired product having a melting point of 103°-108° C. (decomposition) and providing the following analysis:

Workup

customThis compound was prepared by the procedure

Sources & evidence

ORD record: ord-018caaf1f2c54455a53fc19ef55e1a5b
Source dataset: uspto-grants-1986_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04617389

Reaction notes

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