HCID 20229889, compound → HCID 13206444, compound

HRID 2290677Notes

Reaction equation

HRID 2290677 reaction equation
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([O:10][C:11]2[CH:16]=[CH:15][C:14]([C:17]([F:20])([F:19])[F:18])=[CH:13][C:12]=2[Cl:21])=[CH:6][C:5]=1[NH:22][CH2:23][P:24](=[O:33])([O:29]C(C)C)[O:25]C(C)C)([O-:3])=[O:2]>Cl>[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([O:10][C:11]2[CH:16]=[CH:15][C:14]([C:17]([F:18])([F:19])[F:20])=[CH:13][C:12]=2[Cl:21])=[CH:6][C:5]=1[NH:22][CH2:23][P:24](=[O:25])([OH:29])[OH:33])([O-:3])=[O:2]

Participants

3

Reactant 1

HCID 20229889HCID 20229889, compound

Product 1

HCID 13206444HCID 13206444, compound

Reagents, catalysts & solvents 1

HCID 313Hydrochloric AcidSolvent

Procedure

3.0 (5.9 mmoles) of diisopropyl N-[2-nitro-5-(2-chloro-4-trifluoromethylphenoxy)phenyl]-aminomethylphosphonate are refluxed for 16 hours in 100 ml of 20% hydrochloric acid. The solution is concentrated in vacuo, affording 2.3 g (92% of theory) of the title compound in the form of yellow crystals with a melting point of 148°-150° C.

Workup

  1. concentrationThe solution is concentrated in vacuo

Sources & evidence

ORD record
ord-ba937ac9730a4a6397615150538f993c
Source dataset
uspto-grants-1986_10
Patent number
US04618358

Reaction notes

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