HCID 178476823, compound → HCID 178486075, compound

HRID 2290678Notes

Reaction equation

HRID 2290678 reaction equation
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([O:10][C:11]2[CH:16]=[CH:15][C:14]([C:17]([F:20])([F:19])[F:18])=[CH:13][C:12]=2[Cl:21])=[CH:6][C:5]=1[N:22]([CH2:24][PH:25](=[O:29])[O:26]CC)[CH3:23])([O-:3])=[O:2]>Cl>[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([O:10][C:11]2[CH:16]=[CH:15][C:14]([C:17]([F:18])([F:19])[F:20])=[CH:13][C:12]=2[Cl:21])=[CH:6][C:5]=1[N:22]([CH2:24][PH:25](=[O:26])[OH:29])[CH3:23])([O-:3])=[O:2]

Participants

3

Reactant 1

HCID 178476823HCID 178476823, compound

Product 1

HCID 178486075HCID 178486075, compound

Reagents, catalysts & solvents 1

HCID 313Hydrochloric AcidSolvent

Procedure

8.0 g (0.017 mole) of ethyl N-[2-nitro-5-(2-chloro-4-trifluoromethylphenoxy)phenyl]-P-methylaminomethylphosphinate are refluxed for 14 hours in 50 ml of 20% hydrochloric acid. The precipitated crystalline product is isolated and dried at 80° C. in vacuo, affording 7 g (96.8% of theory) of the title compound with a melting point of 153°-154.5° C.

Workup

  1. customThe precipitated crystalline product is isolated
  2. customdried at 80° C. in vacuo

Sources & evidence

ORD record
ord-84aea72513d846c8bf4b368c7ecc4219
Source dataset
uspto-grants-1986_10
Patent number
US04618358

Reaction notes

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